The Tuli Block, a series of privately owned reserves that stretch for 350 kilometres on the south-western border of Botswana, is one of the most accessible parts of Botswana from South Africa, making it an ideal holiday destination. It provides a varied safari experience and allows game to roam without restriction along the entire stretch of land, integrating the Mashatu and Tuli Nature Reserves.

Tuli, which derives its name from a river in Zimbabwe, has a rather interesting frontier history because of its strategic position on the South African border. It was originally intended to form part of Cecil John Rhodes' great railway from Cape to Cairo, but he soon abandoned the idea when he realised how rocky the terrain was. The Tswapong and Lepokde Hills were once home to the San people and rock paintings are prolific in the area. Solomon's Wall, the remains of an ancient dyke, is also worth a visit especially its massive dolerite outcrops, which seem to hem the river in on either side.

Most of the wildlife appears to favour the northern reserves that make up the Tuli Block in Botswana, from wildebeest, kudu, giraffe and zebra, to predators such as cheetah, leopard, jackal and hyena. The rare black-maned lion is a key attraction to the area and the largest elephant population on private land resides in the Tuli Nature Reserves. Birdlife is plentiful with some 350 species having been recorded. Shrikes, boulder chat, raptors and kingfishers are just a few examples. The hot and humid summer months are probably the ideal time to holiday in the Tuli Block, whilst the wettest times are November and December.